One of the phytotherapeutic nutraceutical elements that have fascinated me most in recent years is Ashwagandha (or Withania somnifera, but also called "Indian Ginseng") one of the most powerful herbs in Ayurvedic medicine of which I was among the very first to talk about it in Italy.
In Sanskrit, Ashwagandha means "horse smell", referring to its conferring "the strength and vigor of a stallion". Used for millennia in Ayurvedic medicine, ashwagandha is considered a "Rasayana", a tonic to restore and maintain health and promote longevity. It is attributed known and effective anxiolytic, hypotensive, pain-relieving and antioxidant properties, as well as being used to treat problems related to impotence and infertility.
Today it has come to be increasingly known and appreciated also by the modern "stressed" and adrenaline-pumped Western world, as an "adaptogen" par excellence capable of increasing the body's ability to manage and respond to stressors of various kinds, capable of giving relief , counteract the states of anxiety, to promote relaxation, and mental clarity in case of chronic psychophysical fatigue. The merit of these powerful adaptogenic properties derives from its composition of bioactive elements in the form of steroidal lactones, in this case of "withanolides". First of all "witaferin A", its most powerful active ingredient of this extraordinary medicinal plant to which the various anti-inflammatory, cardioprotective, especially neuroprotective, and immune system activities are attributed.
But its action most recognized and confirmed by research is that on the discourse of the health of the brain, the nervous system and the neurocognitive landscape which extends its potential field of action from only support to states of anxiety and stress. This "cousin" of the tomato improves brain health and function in several ways, such as enhancing the "binding" efficacy of GABA and serotonin receptors in the brain. It seems to act in an interesting way on the receptors of neurons, allowing GABA to connect more easily, and thus inhibit the signals present from the stress response. Tonic-adaptogen therefore par excellence that improves cognitive and psychomotor performance (in a healthy brain), with a particular "antiaging" effect on the axons and dendrites of brain nerve cells, which favors synapses, the junctions in which nerve cells communicate.
We also know that chronic stress and cortisol can damage the brain over time by altering neural networks. Cortisol creates a domino effect that crosses the "software" connection between the hippocampus and the amygdala, the area responsible for your fight or flight response that remains in "permanent alert", even when not needed, or it takes very little to activate it and have a non-proportional response. Here Ashwagandha arrives to intervene precisely to restore those physiological balances and "quell the threats" detected when there is no real need.
If we are experiencing severe fatigue and clouding of the brain ("brain fog"), especially upon waking, if we are perpetually "exhausted" and without strength, if the motivation is on the ground with a fluctuating morale, where anxiety becomes an unpleasant daily burden , Ashwagandha is the most interesting and effective element that oriental phytotherapy has transmitted to us "today", and where modern science has already given several confirmations. An extraordinary nutraceutical element that can be of help to anyone who goes through phases of psychophysical stress, from professionals from various sectors, athletes, military, or anyone who needs to restore "upstream" the ability to respond with clarity and efficiency to agents or stressful situations. mental and physical as well as knowing how to rest when there is no "danger", putting a brake on cortisol levels, with better balance on those of acetylcholine that will reinvigorate performing so you can think again with clarity, more calmly and improving reaction times.
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